History
| Year | Event |
|---|---|
| 2024 | The article on the effect of selective optogenetic activation of the VTA-frontal lobe pathway on the risk-return decision in the macaque monkeys was published in Science. The article on the role of interhemispheric pathway between the premotor cortex in the recovery from partial spinal cord injury was published in Nature Communication. Isa was invited to talk in the Chinese Flagship Neuroscience Symposium “Chang Hsiang-Tung Symposium” in Shanghai. Associate Professor, Ryo Sasaki was appointed to be the professor of National Institute for Physiological Sciences. Project-based Professor, Hirotaka Onoe, was appointed to be the professor of Kobe Gakuin University. Isa’s proposal was accepted by the Brain/MINDS 2.0. Isa was appointed to be the Program Manager of Moonshot Program Goal 7. |
| 2023 | Isa organized the 100th Anniversary Meeting of the Japan Physiological Society as the president. The Associate Professor, Masaaki Ogawa was appointed to be the professor of Shiga University of Medical Science. |
| 2022 | Isa’s research proposal was accepted by Kiban (S) of JSPS. The international symposium by JANUBET was held at the Clock Tower Hall of Kyoto University in person. Isa was appointed to be the Dean of Graduate School of Medicine, Kyoto University. |
| 2021 | The Neurobiology School by the joint project between NTNU Norway, Tohoku and Kyoto Universities, JANUBET (Japan and Norway United in Brain, Educations and Therapeutics”, was held online. |
| 2020 | Isa gave a talk in the Neuroscience Seminar Series of NIH （video can be seen at NIH VideoCast - Neurobiology of recovery after brain and spinal cord injury in macaque models）. Experiments were continued under the Covid-19 pandemic. The article on the collaborative study with Vanduffel Lab at KU Leuven on the pathway-selective blockade of the VTA-Accumbens pathway in macaques was published in Neuron. |
| 2019 | We demonstrated the critical role of the superior colliculus to pulvinar pathway in blindsight by pathway-selective manipulation technique and published the results in Nature Communications (Kinoshita et al. Nat Comm). Grant team for Scientific Research on Innovative Areas “Hyper-adaptability for overcoming body-brain dysfunction: Integrated empirical and system theoretical approaches” was launched, headed by Dr. Jun Ota (Univ Tokyo) |
| 2018 | A project assistant professor, Norihiro Takakuwa received the Tokizane Young Investigator Award. The proposal from Kyoto University to WPI Program was approved and Institute for the Advanced Study of Human Biology was launched, where Tadashi Isa was assigned as the Vice Director. |
| 2017 | Tadashi Isa was assigned as the President of Japan Neuroscience Society. Yukio Nishimura promoted to the Project Leader of Tokyo Metropolitan Institute of Medical Sciences. Our proposal to the Strategic Research Program of Brain Sciences (SRPBC) “Decision Making” was approved. Our proposal to JST/CREST “Optobio” was approved. |
| 2016 | We moved our laboratory to Kyoto University. |
| 2015 | Tadashi Isa moved from NIPS to Kyoto University Graduate School of Medicine. We demonstrated the function of nucleus accumbens during the recovery form spinal cord injury (Sawada et al. Science, 2015). Yukio Nishimura received the 12th JSPS Award. |
| 2014 | Tadashi Isa talked in the Special Lecture of the Society for Neuroscience in Washington DC. The title was “The brain is needed to cure spinal cord injury”. Tadashi Isa received the Kakenhi Kiban (S) for the third time. |
| 2013 | Tadashi Isa received the MEXT Minister Award for Science and technology with Kazuto Kobayashi of Fukushima Medical University and Dai Watanabe of Kyoto University. A PhD student, Kenji Kato, received the SOKENDAI President Award. A project assistant professor, Masaharu Kinoshita received the Young Investigator Award of National Institutes of Natural Sciences. Yukio Nishimura published on the paper on the technology of “artificial neural connection” (in Frontiers in Neural Circuits) and received the Innovative Technologies 2013 special Award from the MITI. |
| 2012 | Yukio Nishimura received the Young Investigator Award from the Minister of MEXT. We succeed in developing the double infection technique of viral vectors for pathway-selective and reversible manipulation technique and regulating the behavior in macaque monkeys for the first time in the world (Kinoshita et al. Nature 2012). |
| 2011 | We organized the 14th Annual Meeting of the Society for Scientific Study of Consciousness (Tadashi Isa served as the Program Committee Chair). Yukio Nishimura received the Young Investigator Award of Japan Physiological Society. |
| 2010 | Tadashi Isa talked in the Special Lecture of FENS Forum held in Amsterdam. Yukio Nishimura received the Young Investigator Award of Japan Neuroscience Society. |
| 2009 | Tadashi Isa served as the president of the 32rd Annual Meeting of the Japan Neuroscience Society. Kasuhiko Seki, an assistant professor, promoted to the group leader of the National Institute for Neurology and Psychiatry. |
| 2008 | Our proposal to the Strategic Research Program of Brain Sciences by MEXT, Program C "Development of creative animal models" was approved and Tadashi Isa became the head of the team. |
| 2007 | We demonstrated the existence of inhibitory pathway from the intermediate to superificial layer of the superior colliculus and published the paper entitled "Identity of a pathway for saccadic suppression" in PNAS. We clarified the change in the cortical activity during the recovery from spinal cord injury, and its contribution to recovery and published the results in Science. |
| 2006 | Tadashi Isa received the 20th Tsukahara Nakaakira Memorial Prize from the Brain Science Foundation. The title was "Motor control circuits; structure, function and recovery from damage".. |
| 2005 | Tadashi Isa’s proposal to HFSP entitled “Neural substrate of bottom-up and top-down attentional integration” with Doug Munoz, Jan Theeuwes and Laurent Itti was approved. |
| 2004 | We organized the NIPS International Symposium entitled “Multidisciplinary Approaches to Sensorimotor Integration” (totally 220 participants including 27 from abroad). We demonstrated that dexterous hand movements can recover after lesion of the corticospinal tract in monkeys (Sasaki et al. J Neurophysiol.) Tadashi Isa participated in the program advisory committee of the 93rd Dahlem Conference entitled “Microcircuits; the interface between neurons and global brain function” held in Berlin. Tadashi Isa’s proposal to CREST, JST “Elucidating the mechanism of brain development and learning” was approved. |
| 2002 | We demonstrated that neurons in the pedunculopontine tegmental nucleus in the monkeys exhibit motivation-related sustained activity (Kobayashi et al. J Neurophysiol). We organized an international workshop entitled “Cognitive Impact on Sensory Motor Integration” in NIPS. Proposal to the National Bio-resource Project “Nihonzaru” (NBR) by Tadashi Isa as PI was approved by MEXT. NBR was launched in NIPS as the primary Institution. |
| 2001 | The research proposal by Tadashi Isa was accepted by the Kiban (S) of Kakenhi Gant from the Ministry of Education, Science and Culture (acceptance rate was 2%). |
| 2000 | The research project entitled "Premotoneuronal interaction between descending pathways; the C3-C4 propriospinal system and reaching" proposed by Tadashi Isa as PI, was accepted by Human Frontier Science Program. |
| 1999 | We demonstrated the existence of disynaptic pyramidal pathway to spinal motoneurons via propsiospinal neurpns in macaque monkeys (Alstermark et al. J Neurophysiol.) We demonstrated that injection of nicotine into the superior colliculus (SC) of monkeys enhanced occurrence of express saccades by facilitation of the SC’S interlaminar pathway (Aizawa et al. J Neurophysiol.) |
| 1998 | We demonstrated the exstence of vertical interlaminar connection in the superior colliculus (Isa et al. J Neurosci 1998). |
| 1996 | Isa Lab started in the National Institute for Physiological Sciences. |